A huntingtin knock-in pig model recapitulates features of selective neurodegeneration in Huntington's disease.
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Cell 2018; 173(4): 989-1002.
γδ T cells provide the early source of IFN-γ to aggravate lesions in spinal cord injury.
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Journal of Experimental Medicine. 2018; 215(2): 521-535.
Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion.
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Nature Neuroscience; 21: 530-540.
Dual extra-retinal origins of microglia in the model of retinal microglia repopulation.
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Cell Discovery; 4: 9.
Flexible Roles for Proteoglycan Sulfation and Receptor Signaling.
PP Yu, CS. Pearson and HM. Geller.
Trends in Neurosciences; 41(1): 47-61.
Next generation histology methods for threedimensional imaging of fresh and archival human brain tissues.
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Nat Commun2018; 9: 1066.
Lycium Barbarum Polysaccharides Protect Retina in rd1 Mice During Photoreceptor Degeneration.
Liu F, Zhang J, Xiang Z, Xu D, So KF, Vardi N, and Xu Y.
IOVS, Jan 59(1): 597-611.
Effect of chondroitin sulfate proteoglycans on neuronal cell adhesion, spreading and neurite growth in culture.
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Identification of novel binding sites for heparin in receptor protein-tyrosine phosphatase (RPTPσ): Implications for proteoglycan signaling.
Katagiri Y, Morgan AA, Yu P, Bangayan NJ, Junka R, Geller HM.
Journal of Biological Chemistry; 293(29): 11639-11647.
Inhibition of non-NMDA ionotropic glutamate receptors delays the retinal degeneration in rd10 mouse.
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Neuropharmacology. 2018 Jun 22. pii: S0028-3908(18)30329-0. doi: 10.1016/j.neuropharm.2018.06.027.
Structural and visual functional deficits in a rat model of neuromyelitis optica spectrum disorders related optic neuritis.
Zhang Y, Bao Y, Qiu W, Peng L, Fang L, Xu Y*, Yang H*.
Exp Eye Res. 2018 Jun 18;175:124-132. doi: 10.1016/j.exer.2018.06.011.
Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Reveal Bradycardiac Effects Caused by Co-Administration of Sofosbuvir and Amiodarone.
Yu Y, Liu F, He L, Ramakrishna S, Zheng M, Bu L*, Xu Y*.
Assay Drug Dev Technol. 2018 May/Jun;16(4):222-229.
Piperine ameliorates SCA17 neuropathology by reducing ER stress.
Jifeng Guo, Yiting Cui, Qiong Liu, Yang Yang, Yujing Li, Ling Weng, Beisha Tang, Peng Jin, Xiao-Jiang Li, Su Yangand Shihua Li*.
Molecular Neurodegeneration. 2018; 30(13):29378605.
Carbon nanotube multilayered nanocomposites as multifunctional substrates for actuating neuronal differentiation and functions of neural stem cells.
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Biomaterials. 2018; 175:93-109.
Distinct multi-level misregulations of Parkin and PINK1 revealed in cell and animal models of TDP-43 proteinopathy.
Sun X*, Duan Y*, Qin C, Li JC, Duan G, Deng X, Ni J, Cao X, Xiang K, Tian K, Chen CH, Li A#, Fang Y#.
Cell Death & Disease. 2018; 9(10): 953.
CRISPR/Cas9-mediated disruption of SHANK3 in monkey leads to drug-treatable autism-like symptoms.
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Human Molecular Genetics. 2018; 28(4): 561-571.
Distribution and functional implication of secretin in multiple brain regions.
Wang R, BKC Chow* and Zhang L*.
Journal of Molecular Neuroscience. 2018 Jun 07. doi: 10.1007/s12031-018-1089-z.
Activating Adiponectin Signaling with Exogenous AdipoRon Reduces Myelin Lipid Accumulation and Suppresses Macrophage Recruitment after Spinal Cord Injury.
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Journal of Neurotrauma. 2018 Oct. doi: 10.1089/neu.2018.5783.
Aberrant Development and Synaptic Transmission of Cerebellar Cortex in a VPA Induced Mouse Autism Model.
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Frontiers in Cellular Neuroscience. 2018; 12: 500.
